Express Scripts is a Missouri-based pharmacy benefit management company and is one of Missouri’s largest corporations. Nexus Group has represented Express Scripts since 2009. ESI and other PBMs exist to ensure that their customers (businesses, organizations and governments) are getting the very best pharmacy benefits and technology for their employees. Often this cuts into the profits of independent pharmacists and pharmaceutical manufacturers. As a result, each year, pharmacists and pharmaceutical manufacturers try to disrupt the PBM business model.